Club cells, also known as Clara cells, are a type of non-ciliated, secretory epithelial cell found in the lining of the respiratory tract. These cells play a key role in protecting the lungs from environmental toxins and pathogens by producing and secreting several important proteins and enzymes. Club cells are known for their unique shape and function in maintaining lung homeostasis, and are particularly important in the repair and regeneration of damaged respiratory epithelium. Research on club cells focuses on understanding their role in lung function, disease, and repair processes, as well as their potential therapeutic applications in respiratory disorders.